Title: Experiences from an international intercalibration of dioxin-like compounds in cod liver using bioassays

Auteur(s): Engwall M ; Lindstrom G ; Van Bavel B ;  ; 

Year: 2003

Journal: Organohalogen Compounds

Subject(s): bioassay ; dioxin-like compounds ; food ; analysis ; fly ash ; Coplanar PCBs ; PCBs ; PCB ;  ; 

Summary: This intercalibration study is an international exercise to validate the use of bioassays to determine levels of dioxin-like compounds in food. It was open for academic, regulatory and commercial laboratories. A full report of the intercalibration, which also includes bioassay analysis of fly ash and fly ash extract, is available from the authors. The study, performed during 2002 attracted considerable interest, and initially we received registrations from 18 laboratories world-wide. The objectives of the study were: 1) to estimate the agreement between bioassay results and GC/MS-determined levels ofPCDDs, PCDFs and coplanar PCBs in acod liver sample, 2) to study differences in sensitivity between different bioassays, 3) to assess interlaboratory variation for similar bioassays.