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A comparative study of GC-HRMS and CALUX TEQ determinations in food samples by the Belgian federal ministries of public health and agriculture



A comparison of toxicity equivalency (TEQ) results obtained using rapidscreen and the DIPS-CALUX bioassay with EPA method 8290 and 1668A calculated TEQS



A novel in vivo bioassay for (xeno-) estrogens using transgenic zebrafish.



A novel low-cost air sampling device(AmbStack sampler) and detection system (CALUX bioassay) for measuring air emissions of dioxin, furan and PCB on a TEQ basis tested with a model industrial boiler



Additive genetic variation of transcriptional regulation: metallothionein expression in the soil insect Ochesella cincta



Ah receptor-mediated luciferase expression: A tool for monitoring dioxin-like toxicty



Alternate extraction and clean-up for CALUX® analyses of feeds and feed components



An in vitro rainbow trout cell bioassay for Ah receptor-mediated toxins



An innovative injury quantification approach for organisms exposed to AhR-active compounds



Analysis and occurrence of estrogenic hormones and their glucuronides in surface water and waste water in The Netherlands



Analysis of brominated flame retardants and brominated dibenzodioxins and biphenyls for Ah receptor activation using the CALUX bioassay



Analysis of PCB-congeners (by GC-ECD) and dioxin-like toxic equivalence (by CALUX assay) in females with endometriosis and other fertility problems



Analysis of PCDD/FS in human blood plasma using CALUX bioassay and GC-HRMS: A comparison



Analysis of polychlorinated dibenzo-p-dioxins (PCDD), dibenzofurans (PCDF) and biphenyls (PCB) in fish using DR-CALUX® and GC/MS: a comparison



Antagonistic effects of mono- and di-ortho-substituted PCBs in the EROD activity and the luciferase reporter gene assay in vitro



Application of 'alternative' methods for dioxin monitoring - shifting the paradigm



Application of a steroid receptor-based battery of CALUX bioassays for water quality control analysis



Application of biomarkers for exposure and effects of polyhalogenated aromatic hydrocarbons in naturally exposed European otters (Lutra lutra)



Application of in vitro and in vivo reporter gene assays for assessing (mixtures of ) estrogenic substances



Application of the CALUX (chemically activated luciferase gene expression) assay for measuring TCDD-equivalents in sediment, pore water, and blood samples



Application of the CALUX bioassay for quantification of dioxin-likecompounds in small amounts of human milk and blood plasma



Application of the CALUX bioassay for the determination of low TEQ values in milk samples



Application of the CALUX bioassay system for the detection of dioxin-like chemicals (Ah receptor ligands) in whole serum samples and in extracts from commercial and consumer products



Application of the CALUXTM assay to the analysis of DXNS in a composite from sushi samples (The third report)



Applications of in vitro screening tools to support tisk assessment of brominated flame retardants



Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay



Assessing the estrogenic and dioxin-like activities of chemicals and complex mixtures using in vitro recombinant receptor-reporter gene assays



Atmospheric input of polychlorinated biphenyls to the eastern Mediterranean



Autoinduction of retinoic acid metabolism to polar derivatives with decreased biological activity in retinoic acid-sensitive, but not in retinoic acid-resistant human breast cancer cells



Behavior of dioxins and the relevance to soil characteristics in a river basin of Lake Biwa, Japan



Bio/chemical analysis of dioxin-like compounds in sediment samples from Osaka Bay, Japan



Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons



Bioanalytical detection methods (BDMs) and monitoring



Bioanalytical screening methods for dioxins and dioxin-like compounds - a review of bioassay/biomarker technology



Bioassay for monitoring dioxins in foods and feeds



Bioassay monitoring study in the PCB degradation process using metallic sodium dispersion



Bioassays for the detection of growth-promoting agents, veterinary drugs and environmental contaminants in food



Biodetectors in environmental chemistry: Are we at a turning point? Editorial



Biological in vitro investigation of PBT in industrial and environmental samples



Biological measurement of estrogenic activity in urine and bile conjugates with the in vitro ER CALUX reporter gene assay



Biological screening of Ah receptor agonist activity in butter fat and coconut oil by means of chemical-activated luciferase expression in a genetically engineered cell line (CALUX)



Biological validation of a sample preparation method for ER CALUX bioanalysis of estrogenic activity in sediment using mixtures of xeno-estrogens



Biomonitoring of estrogenic exposure and identification of responsible compounds in bream from Dutch surface waters



Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds



CAFLUX, a simplified version of the CALUX assay for Ah receptor (ant)agonists based on enhanced green fluorescent protein (EGFP) reporter gene expression



CALUX and high resolution GC/MS analysis of dioxin-like compounds in chlorophenoxt pesticide formulations



CALUX results correlate with GC/MS data from kazakstan breast milk samples and support new TEF values



CALUX® reporter cell lines as sensitive bioassays for monitoring biological activity of various classes of steroid hormones reveal the repressive effect of TCDD on the estrogen receptor



Characterization of the interaction of transformed rat hepatic cytosolic Ahreceptor with a dioxin responsive transcriptional enhancer



Chemical carcinogens induce varying patterns of LOH in mouse T-lymphocytes



Chemical-activated luciferase gene expression (CALUX): a novel in vitro bioassay for Ah receptor active compounds in sediments and pore water



Combinatorial bio/chemical analysis of dioxin and dioxin-like compounds in waste recycling, fee/food, humans/wildlife and the environment



Commission decision of […] laying down performance criteria for the analytical methods to be used for certain substances and residues thereof in live animals and animal products according to Council Directive 96/23/EC



Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: Implications for their use as bioanalytical tools for the detection of ployhalogenated aromatic hydrocarbons



Comparison of CALUX-TEQ values with PCB and PCDD/F measurements in human serum of the Flanders Environmental and Health Study (FLEHS)



Comparison of CALUX-TEQs and levels of PCDD/F and PCB in SFE-extracts of human adipose tissue



Comparison of Chemical-Activated Luciferase Gene Expression Bioassay and Gas Chromatography for PCB Determination in Human Serum and Follicular Fluid



Comparison of dioxin and PCB concentration in human breast milk between Hong Kong and The Netherlands



Comparison of DR-CALUX- and HRGCMS-derived TEQS: Introduction of conversion factors



Comparison of in vitro and in vovo screening models for androgenic and estrogenic activities



Comparison of in vivo and in vitro reporter gene assays for short-term schreening of estrogenic activity



Comparison of the CALUX bioassay and ID-HRGC/HRMS as measures of dioxin toxic equivalents in serum



Contemporary relevance of dioxin and dioxin like compound contaminations in residues from recycling of HCH waste



Control analysis of eel using CALUX and GC/MS



Control of bovine milk samples by CALUX bioassay and GC-HRMS analysis



Council Regulation (EC) 2001/102/EC of 27 November 2001 amending Directive 1999/29/EC on the undesirable substances and products in animal nutrition



Council Regulation (EC) No 2375/2001 of 29 November 2001 amending Commission Regulation (EC) No 466/2001 setting maximum levels for certain contaminants in foodstuffs



Cross-validation study of the DR-CALUX®-bioassay Comparison to Micro-EROD bioassay and chemical analyses



CYP2C7 expression in rat liver and hepatocytes: regulation by retinoids.,



Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays



Detection of estrogenic activity of steroids present during mammalian gestation using ERa and ERß specific assays



Detection of estrogenic potency in wastewater and surface water with three in vitro bioassays



Determination and multivariate statistical analysis of biochemical responses to environmental contaminants in feral freshwater fish Leuciscus cephalus L



Determination of dioxins (PCDDs/PCDFs) and PCBs in food and feed using the DR CALUX bioassay: Results of a validation study



Determination of dioxins and planar PCBs in fish using the GC/MS and CALUX bioassay: introduction of the screening approach for control purposes



Determination of REP values by DR CALUX® and micro-erod for several PCDD/FS and Co-PCBs and comparison to WHO TEF values (1998)



Determination of REP values for the CALUX bioassay and comparison to the WHO TEF values



Determination of the endocrine disrupting potency of hydroxylated PCBs and Flame Retardents with in vitro bioassays



Development of a reference dose for the persistent congeners of weathered toxaphene based on in vivo and in vitro effects related to tumor promotion



Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line



Development of a toxicological gene array and quantitative assessment of this technology



Development of androgen- and estrogen-responsive bioassays, members of a Panel of Human Cell Line-based highly selective steroid-responsive bioassays



Development of bio-monitoring tool in waste wood recycling using the CALUX assay



Development of improved DR-CALUX bioassay for sensitive measurement of aryl hydrocarbon receptor activating compounds



Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachloribiphenyl (4-OH-CB107): Lond-term effects on brain development, behanvior, and brain stem auditory evoked potentials in rats



DIFFERENCE: Optimisation and validation of screening methods for the analysis of dioxins and dioxin-like PCBS in food and feed and the production of certified reference materials



Dioxin and PAH in chimney soot from domestic heating appliances with solid fuels



Dioxin monitoring by a cell-based Ah receptor bioassay for a low-temperature thermal dechlorination process



Dioxin monitoring by a cell-based Ah receptor bioassay for low-temperature thermal dechlorination process



Dioxin-like and transthyretin-binding compounds in indoor dusts collected from Japan: Average daily dose and possible implications for children



Dioxin-like PCBs released from waste incineration and their deposition flux



DR and ER CALUX assays as tools to direct toxicity identification and evaluation of endocrine disrupting chemicals



DR-CALUX® interlaboratory validation study for sediments.



DR-CALUX®- and EROD-TEF values for dioxin-like compounds (PXBs/PXDDs/Fs; X=Br, Cl) and others (e.g. PAHs)



DRE-CALUX bioassay in comparison with HRGC/MS for measurement of toxic equilvalence in environmental samples



Effects of currently used pesticides in the AhR-CALUX assay: comparison between the human TV101L and the rat H4IIE cell line



Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous clyclicity in rats



Effects of oxfendazole on the Ah receptor-mediated induction of ethoxyresorufin-O-deethylase and luciferase activity by 2,3,7,8,- tetrachlorodibenzo-p-dioxin in Hepa-1c1c7 and H4IIE cell-lines



Effects of retinoic acid on the 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced differentiation of in vitro cultured human keratinocytes



Embryonal carcinoma cell lines stably transfected with mRARbeta2-lacZ: sensitive system for measuring levels of active retinoids



Endocrine Disruption. Biological Bases for Health Effects in Wildlife and Humans



Environmental impact and recovery at two dumping sites for dredged material in the North Sea



Estimating the total TEQ in human blood from naturally-occurring vs. anthropogenic dioxins: A dietary study



Estrogen and dioxin-like compounds in sediment from Zierikzee harbour identified with CALUX assay-directed fractionation combined with one and two dimensional gas chromatography analyses



Estrogenic activity of UV screens determined by an in vitro reporter gene assay and an in vivo transgenic zebrafish assay



Estrogenic and dioxin-like activity in diesel exhaust



Evaluation of mixture effects in a crude extract of compost using the CALUX bioassay and HPLC fractionation



Evaluation of the DR-CALUX bioassay for the determination of dioxins in food and feed according to the requirements of the Commission Directives 2002/69 AND 2002/70 respectively



Evidence for estrogenic and TCDD-like activities in extracts of blood and semen of men



Experiences from an international intercalibration of dioxin-like compounds in cod liver using bioassays



Exposure of workers to 2,3,7,8-substituted polychlorinated dibenzo-p-dioxin (PCDD) and dibenzofuran (PCDF) compounds in sawmills previously using chlorophenol-containing antistain agents.



Expression of CYP1A1 and 1B1 MRNA in blood lymphocytes from two district populations in Slovakia compared to total TEQS in blood as measures by the DRE-CALUX® ASSAY



Expression of retinoic acid 4-hydroxylase (CYP26) during mouse and Xenopus embryogenesis.,



Follow-up assessment of PCDD/PCDF in eggs from allotments in NewCastle upon Tyne England



FORUM - Reevaluation of the cancer potency factor of toxaphene: Recommendations from a peer review panel



FORUM: Concise Review: Gene Expression Applied to Toxicology



Fractionation of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and planar polychlorinated biphenyls by high performance liquid chromatography on a pyrenyl-silica column



Functional aspects of development toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants



Genomics Tools in Environmental Impact Assessment



Glucocorticoid mediated expression of dioxin target genes in rat H4IIE cells but not in human HEPG2 and T47D cells



Hagenmaier drum - fly ash Dechlorination/ hydrogenation process: Combinatorial bio/chemical analysis



Harmonised quality criteria for chemical and bioassays Analyses of PCDDS/PCDFS in feed and food Part 2: General considerations, BIOASSAY methods



Harmonised quality criteria for chemical and bioassays analyses of PCDDs/PCDFs in feed and food. Part 1: General considerations, GC/MS methods



Health risks from dioxins and related compounds: principal conclusions and recommendations of a French expert advisory group (2000)



Human chromosome 11 suppresses the tumorigenicity of adenovirus transformed baby rat kidney cells: involvement of the Wilms' tumor 1 gene.,



Human colon microbiota transform polycyclic aromatic hydrocarbons to estrogenic metabilites



Human retinoic acid 4-hydroxylase (CYP26) is highly specific for all-trans RA, and can be induced through retinoic acid receptors in human breast and colon carcinoma cells.,



Improved sample preparation method for selected persistent organochlorine pollutants in human serum using solid-phase disk extraction with gas chromatographic analysis



Improvement of chemically-activated luciferase gene expression bioassay for detection of dioxin-like chemicals



In vitro antiestrogenic effects of environmentally persistent methyl sulfone metabolites of 2,2',4,5'-Tetrachlorobiphenyl and 2,2',4,5,5'-Pentachlorobiphenyl: Inhibition of 17ß-estradiol-induced gene expression in several bioassay systems.



In vitro estrogenicity of brominated diphenyl ethers (PBDEs), hydroxylated PBDEs and polybrominated bisphenol A compounds



In vitro profiling of the endocrine-disrupting potency of brominated flame retardants



In vitro recombinant receptor/reporter gene assays for assessing the estrogenic and dioxin-like activity of compounds and complex mixtures



Induction and repair of DNA single-strand breaks and DNA base damage at different cellular stages of spermatogenesis of the hamster upon in vitro exposure to ionizing radiation



Influence of arsenic co-contamination on DDT breakdown and microbial activity



Instrumental and bioanalytical measures of dioxin-like activity in sediments from Masan Bay, Korea



Inter-laboratory CALUX® comparison data at low levels with traditional GC-HRMS confirmations



Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor b



Intra- and Interlaboratory calibration of the DR CALUX bioassay for the analysis of dioxins and dioxin-like chemicals in sediments



Introduction of a linear 2,3,7,8,-TCDD curve-fit as a means to improve performance characteristics of the DR CALUX bioassay



Levels of PCDD/PCDFs and dioxin-like PCBs in different feed materials of plant origin from Germany



Low-temperature thermal decomposition of dioxin-like compounds in fly ashes: Combination of chemical analysis with in vitro bioassays (EROD and DR CALUX)



Manure-borne estrogens as potential environmental contaminants: A review



Metabolism of retinoic acid: Implications for development and cancer



Monitoring river sediments contaminated predominantly with polyaromatic hydrocarbons by chemical and in vitro bioassay techniques



Morphogenic actions of retinoids and estrogens



Mouse Mismatch repair gene Msh2 is not essential for Transcription-coupled repair of UV-induced Pyrimidine Dimers



Non additive interactions in CALUX



Observation of an extremely high dioxin level in a human serum sample from Ukraine by DR CALUX wich was confirmed to be 2,3,7,8-tetrachlorodibenzo-p-dioxin by GC-HRMS



Optimised extraction and fine tuned chemical and bioanalytical determination of organohalogens in human samples



PCB Destruction by catalytic hydrodechlorination (CHD) and t-BuOK Method: Combinatorial bio/chemical analysis



PCDD/PCDF: human background data for Germany, a 10 year experience



Perfluoroalkyl acids have no endocrine disruping activities via human steroid hormone receptors as determined by a panel of CALUX bioassays



Persistent organic pollutants and immune function in US Atlantic coast harbor seals (PHOCA VITULINA CONCOLOR )



Persistent organochlorine compounds in human serum of 50-65 years old women living in two regions of Flanders, Belgium,



Practical CALUX-monitoring of PCB wastes during their chemical dechlorination treatments



Production of a novel recombinant cell line for use as a bioassay system for detection of 2,3,7,8-TCDD-like chemicals



Production of novel recombinant cell line bioassay systems for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals



Prolonged progestin treatment induces the promoter of CDK-inhibitor p21Cip1, Waf1 through activation of p53 in human breast- and endometrial tumor cells



Quality control criteria implemented for monitoring the use of the CALUX bioassay



Ranking the bioassay TEFs ajd REPs



Relative potencies (REPs) of several Ah receptor agonists measured by two cell bioassays



Relative potencies of Halowax mixtures and indiviudal PCNs to induce Ah receptor-mediated responses in the rat hepatoma H4IIE-luc cell bioassay



Renal function, cytogenetic measurements, and sexual development in adolescents in relation to environmental pollutants: a feasibility study of biomarkers,



Report of the WHO working group onthe assessment of health risks for human infants from exposure to PCDDs, PCDFs and PCBs



Response of human CYP1-luciferase plasmids to 2,3,7,8-TCDD and polycyclic aromatic hydrocarbons



Results of the first International Interlaboratory DR CALUX® by BDS comparison study for food and feed (BICS 2005)



Retinoic acid hydroxylase (CYP26) is a key enzyme in neuronal differentiation of embryonal carcinoma cells



Retinoic acid metabolism: cause or consequence of RA action? A dual role for cytochrome P450 retinoic acid hydroxylase CYP26



REVIEW - The 2005 World Health Organizatio Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds



Review of analytical methods for the determination of estrogens and progestogens in waste waters



Sample preparation method for the ER CALUX bioassay screening of (xeno-)estrogenic activity in sediment extracts



Screening of dioxin-like toxicity equivalents (TEQs) for various matrices with wildtype (EROD) and recombinant (DR-CALUX) rat hepatoma H4IIE cells



Selective adsorption of dioxins and PCB's from marine oils on activated carbon



Separation of non-ortho polychlorinated biphenyl congeners on pre-packed carbon tubes. Application to analysis in sewage sludge and soil samples



Simplified sample preparation methods for rapid immunoassay analysis of PCDD/Fs in foods



Species-specific antagonism of Ah receptor action by 2,2',5,5'-tetrachloro- and 2,2',3,3',4,4'-hexachlorobiphenyl



Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals



Studies of the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of the retinoid system using retinoid pathway knockout mice



Substance flow analysis of coplanar PCBs released from waste incineration processes



Suitability of several carbon sorbents for the fractionation of various sub-groups of toxic polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans



Superinduction in the DR-CALUX bioassay by extracts from soil samples taken during a soil bioremediation process



Surrogates for dioxin analyses: analytical, ELISA and toxicological aspects



Synergistic effect of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic porphyrin levels in the rat



Targeted disruption of the mouse Rev3 gene results in embryonic lethality accompanied by apoptotic catastrophe



Textbook of Medical Physiology



The application of reporter gene assays for the determination of the toxic potency of diffuse air pollution



The CALUX assay adapted and validated for measuring TCDD equivalents in blood plasma



The Chimeric VirA-Tar Receptor Protein is Locked into a Highly Responsive State



The distribution of endogenous retinoic acid in the chick embryo: Implications for developmental mechanisms.,



The effect of 9-cis-retinoic acid on proliferation and differentiation of A spermatogonia and retinoid receptor gene expression in the vitamin A-deficient mouse testis



The expression of CYPIA, vitellogenin and zona radiata proteins in Atlantic salmon (Salmo salar) after oral dosing with two commercial PBDE flame retardant mixtures: absence of short-term responses



The principles and practice of tocxicogenomics:



The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: A comparison with pentachlorobenzene in a 13-week feeding study



Tissue- and time-dependent estrogen receptor activation in estrogen reporter mice



Toxic equivalency factors (TEFs) for halogenated aromatic hydrocarbons in wildlife



Toxicological profiling of sediments using in vitro bioassays, with emphasis on endocrine disruption



Trace contamination with dioxin-like chemicals: evaluation of bioassay-based TEQ determination for hazard assessment and regulatory responses



Tracing endocrine disruptors. Identification and effects of endocrine disrupting compounds in the aquatic environment



Transcriptional activation of estrogen receptor a (ERa) and ERß by polycyclic musks is cell-type dependent,



Tumour promotion by complex mixtures of dioxin and non-dioxin like polyhalogenated aromatic hydrocarbons



Using the CALUX bioassay for screening and determination of dioxin-like compounds in human milk



Using the dioxin receptor-CALUX in vitro bioassay to screen marine harbor sediments for compounds with a dioxin-like mode of action



Validation and discussion of CALUX analysis for marine samples



Validation and use of the CALUX-bioassay for the determination of dioxins and PCBs in bovine milk



Validation of extraction, clean-up and DR CALUX bioanalysis. Part I: foodstuff



Validation of extraction, cleanup and DR CALUX bioanalysis. Part I: feedingstuff



Validation of the ERa CALUX bioanalysis for the determination of estrogenic activity in human plasma



Validation study for practical bio-monitoring of waste PCB samples during their destruction treatment using DR CALUX® assay and PCB immunoassay



Validation study for the use of the dioxin responsive CALUX assay for analysis of Japanese ash and soil samples



Vertical profile of dioxin-like and estrogenic potencies in a sediment core from Tokyo Bay, Japan



Vertical profile of dioxin-like and estrogenic potencies in a sediment core from Tokyo Bay, Japan



Vertical profiles of dioxin-like and estrogenic activities associated with a sediment core from Tokyo Bay, Japan



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