DR CALUX®
dioxins
mode/action
bioassay
procedure
properties
ER CALUX®
estrogens
mode/action
bioassay
procedure
properties
Estradiol , a female sex hormone, has a direct effect on the function of the reproductive system, the nervous system, the cardiovascular system and the skeletal system.
Blood sugar levels, skin and other tissues and functions are also significantly influenced by estradiol. Like all steroid hormones, excessive amounts of estradiol can contribute to a number of increased health risks. An increasing number of reports that chemicals in the environment mimic the natural estrogen thereby disrupting normal endocrine function, have raised public concern. It has been hypothesised that increased incidence of hormone-sensitive cancers, decreased sperm counts in humans, and compromised gonadal functionality in wildlife is due to exposure to substances possessing estrogenic activity.
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