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| BREAKTHROUGH - DIOXINS ANALYSIS IN
BLOOD |
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| Mai 2004 |
Mai 26, 2004 - Using BioDetection System BV’s innovative DR CALUX®
bioassay, dioxin and dioxin-like compound levels can now be measured
in just 2 mls of serum or 4 mls of whole blood.
Using BioDetection System BV’s innovative DR CALUX® bioassay,
dioxin and dioxin-like compound levels can now be measured in just
2 mls of serum or 4 mls of whole blood.
As a result of extensive R&D work, BDS has applied the very high sensitivity
of its innovative DR CALUX® bioassay to the analysis
of dioxins and dioxin-like compounds in human blood. Processing
just 4mls of whole blood or 2 mls of serum, we are able to achieve
a limit of quantitation of 20 pg TEQ/g lipid (LOD = 7 pg TEQ/g).
By capturing the low end of the human dioxins in blood range,
epidemiological studies of individual human blood dioxin levels
using very small blood volumes is now practical.
Previously, similar analysis by HRGCMS has typically required 50 - 200 mls of
blood in order to achieve adequate detection levels. This
has meant that studies have often been limited to using pooled blood
samples or special circumstances where large blood volumes could
be justified.
With this latest development, blood dioxin levels can readily be measured in
discreet individual adults and potentially practically for the first
time in infants.
High sensitivity in BDS' DR CALUX® bioassay, combined with low cost
(ca. Euro 240 per analysis) provides the future tool of choice for
dioxins epidemiology work.
BDS will be presenting information on this latest development in the proceedings
and at its exhibition booth at the annual Dioxin conference in Berlin
between 6 – 10 September 2004 (www.dioxin2004.org).
For information before then, call us on +31 20 4350 750
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