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Bioassays

BDS offers an extensive panel of high-throughput-compatible CALUX® reporter assays that enable effect identification and effect-based compound detection. Our assays allow for the sensitive and precise detection of specific biological effects at the cellular level. The panel contains assays relating to various effect classes such as endocrine disruption, xenobiotics metabolism, genotoxicity and acute toxicity. The influence of metabolic conversion of the samples may optionally be included in the test by the addition of metabolic enzymes. An overview of the CALUX® assays that are currently available is presented here. CALUX® analyses are performed in the BDS service laboratory, but are also run under license by others.